3D Micropillars Guide the Mechanobiology of Human Induced Pluripotent Stem Cell-Derived Cardiomyocytes.
basic_science · Level V
Where this comes from
- Record sourced from PubMed, PMID 26676091.
- Also identified by DOI 10.1002/adhm.201500740.
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Abstract
3D micropillars generated by photolithography are used as a platform to probe by atomic force microscopy the mechanodynamics of human induced pluripotent stem cell-derived cardiomyocytes. 3D micropillars guide subcellular cytoskeletal modifications of cardiomyocytes and lead to biochemical changes altering beating rate, stiffness, and calcium dynamics of the cells.
Medical subject headings
- Induced Pluripotent Stem Cells
- Myocytes, Cardiac