Use of the Novel Therapeutic Agent Miltefosine for the Treatment of Primary Amebic Meningoencephalitis: Report of 1 Fatal and 1 Surviving Case.
case_report · Level V
Where this comes from
- Record sourced from PubMed, PMID 26679626.
- Also identified by DOI 10.1093/cid/civ1021 and PMC identifier 4775347.
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Abstract
Primary amebic meningoencephalitis (PAM) is a fulminant central nervous system infection caused by the thermophilic free-living ameba Naegleria fowleri. Few survivals have been documented and adequate treatment is lacking. We report 2 PAM cases, 1 fatal and 1 surviving, treated with the novel antiparasitic agent miltefosine.
Medical subject headings
- Antiprotozoal Agents
- Central Nervous System Protozoal Infections
- Naegleria fowleri
- Phosphorylcholine