Scientific Significance of Clinically Insignificant FcγRIIIa-V158F Polymorphism.
editorial · Level V
Where this comes from
- Record sourced from PubMed, PMID 26683631.
- Also identified by DOI 10.1158/1078-0432.CCR-15-2777.
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Abstract
Kenkre and colleagues report the absence of correlation between FcγRIIIa-V158F polymorphism and rituximab response in follicular lymphoma patients, a result which is in contrast with prior studies. This discrepancy recalls that many other factors (from the host and from the tumor) may influence the efficacy of rituximab in vivo.
Medical subject headings
- Antibodies, Monoclonal, Murine-Derived
- Receptors, IgG