Rapid Reversible Photoswitching of Integrin-Mediated Adhesion at the Single-Cell Level.
basic_science · Level V
Where this comes from
- Record sourced from PubMed, PMID 26685922.
- Also identified by DOI 10.1002/adma.201504394.
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Abstract
Rapid and reversible photoswitching of cell adhesion is achieved by c(RGDfK)-azobenzenes embedded in a poly(ethylene glycol) background on surfaces. The light-induced cis-trans-isomerization of the azobenzene enables switching of cell adhesion on the surface. Reversibility of switching over several consecutive switching cycles is demonstrated by single-cell force spectroscopy.
Medical subject headings
- Integrins
- Light