Drug the Bug!
basic_science · Level V
Where this comes from
- Record sourced from PubMed, PMID 26687345.
- Also identified by DOI 10.1016/j.cell.2015.12.005.
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Abstract
Microbial metabolism of dietary components has been causally linked to cardiovascular disease and atherosclerosis. Now, Wang et al. demonstrate that inhibition of microbial TMA lyases, essential for production of pro-atherogenic trimethylamines, prevents atherosclerosis in vivo.
Medical subject headings
- Atherosclerosis
- Choline
- Gastrointestinal Tract
- Hexanols
- Lyases
- Methylamines