Not All Created Equal: Lineage Hard-Wiring in the Production of Blood.
basic_science · Level V
Where this comes from
- Record sourced from PubMed, PMID 26687347.
- Also identified by DOI 10.1016/j.cell.2015.12.013.
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Abstract
The multiple cell types comprising blood have been thought to emerge from progenitors with progressively narrower lineage options. New data suggest that lineage fate may be determined earlier than thought and that myeloid progenitor populations are aggregates of individual lineage-restricted cells.
Medical subject headings
- Cell Lineage
- Hematopoiesis
- Myeloid Progenitor Cells
- Single-Cell Analysis
- Transcriptome