SnapShot: Interferon Signaling.
review · Level V
Where this comes from
- Record sourced from PubMed, PMID 26687364.
- Also identified by DOI 10.1016/j.cell.2015.12.008.
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Abstract
Interferons (IFNs) are crucial cytokines of antimicrobial, antitumor, and immunomodulatory activity. The three types of IFN (I, II, and III) are classified by their receptor specificity and sequence homology. IFNs are produced and secreted by cells in response to specific stimuli. Here, we review the subsequent IFN signaling events occurring through unique receptors leading to regulation of gene expression for modulation of innate and adaptive immunity. To view this SnapShot, open or download the PDF.
Medical subject headings
- Interferons
- Signal Transduction