Are Astrocytes the Pressure-Reservoirs of Lactate in the Brain?

Kasparov, Sergey · Cell Metab · 2016

other · Level V

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Abstract

The role of lactate in the brain has been controversial. In this issue, Mächler et al. (2015) present data from in vivo experiments suggesting that there is a downward gradient of lactate in the brain. They provide a mechanistic basis for the proposed export of lactate from astrocytes to neurons.

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