Cancer: Oncogene brought into the loop.
basic_science · Level V
Where this comes from
- Record sourced from PubMed, PMID 26700812.
- Also identified by DOI 10.1038/nature16330 and PMC identifier PMC3656605.
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Abstract
Analysis of the 3D structure of DNA in tumour cells reveals how mutations in the IDH1 gene, and associated changes in methyl groups attached to DNA, elevate the expression of cancer-promoting genes.