OfftargetFinder: a web tool for species-specific RNAi design.
basic_science · Level V
Where this comes from
- Record sourced from PubMed, PMID 26704598.
- Also identified by DOI 10.1093/bioinformatics/btv747.
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Abstract
RNA interference (RNAi) technology is being developed as a weapon for pest insect control. To maximize the specificity that such an approach affords we have developed a bioinformatic web tool that searches the ever-growing arthropod transcriptome databases so that pest-specific RNAi sequences can be identified. This will help technology developers finesse the design of RNAi sequences and suggests which non-target species should be assessed in the risk assessment process. http://rnai.specifly.org crobin@unimelb.edu.au.
Medical subject headings
- Databases, Genetic
- Internet
- RNA Interference
- Transcriptome