Does Body Mass Index Decrease Over Time Among Patients Who Undergo Total Knee Arthroplasty Compared to Patients With Osteoarthritis? Data From the Osteoarthritis Initiative.

Abstract

Although total knee arthroplasty (TKA) is associated with improved patient-reported function, pain, and quality of life, the effects on weight loss are less certain. In this study, we use data from a large, prospective cohort study of osteoarthritis (OA) patients to compare the changes in body mass index (BMI) across 6 years in OA patients who received TKA compared with OA patients who did not receive TKA. Using data from the Osteoarthritis Initiative, a prospective cohort study of patients with OA, our study divided patients into two groups: patients who received a TKA during the Osteoarthritis Initiative study (N = 140) and those who did not (N = 697). The initial BMI, final BMI, and change in weight over 72 months were compared between groups. Subgroup analysis was performed by dividing patients by their initial BMI, gender, and age. The TKA group's change in weight, initial BMI, and final BMI were not significantly different from the non-TKA group over 72 months (weight change: -0.763 kg vs +0.191 kg; P = .597). Subgroups of women and patients aged 51-60 years with TKA gained more weight than respective non-TKA OA patients. Overall, patients who received TKA did not lose or gain more weight than OA patients who did not receive TKA. Patients with longer follow-up after TKA (>2 years) still gained weight on average. Despite the improved patient-reported pain levels, function, and quality of life after TKA, it appears that TKA alone is not a sufficient intervention for obesity.