Path2PPI: an R package to predict protein-protein interaction networks for a set of proteins.

Philipp, Oliver; Osiewacz, Heinz D; Koch, Ina · Bioinformatics · 2016

basic_science · Level V

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Abstract

: We introduce Path2PPI, a new R package to identify protein-protein interaction (PPI) networks for fully sequenced organisms for which nearly none PPI are known. Path2PPI predicts PPI networks based on sets of proteins from well-established model organisms, providing an intuitive visualization and usability. It can be used to combine and transfer information of a certain pathway or biological process from several reference organisms to one target organism. Path2PPI is an open-source tool implemented in R. It can be obtained from the Bioconductor project: http://bioconductor.org/packages/Path2PPI/ CONTACT: : ina.koch@bioinformatik.uni-frankfurt.de Supplementary data are available at Bioinformatics online.

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