Illuminating inflammasome activity in vivo.
basic_science · Level V
Where this comes from
- Record sourced from PubMed, PMID 26735405.
- Also identified by DOI 10.1038/nm.4026 and PMC identifier 6369000.
- No licence information is recorded for this record.
- Because redistribution is not established, this page shows the abstract only. Follow the links below for the full text.
Abstract
Sentinel macrophages in the lymph node provide a first line of defense against invading viruses. A new study visualizes inflammasome activation in virally infected nodal macrophages in mice and shows that this activation augments both innate and adaptive immunity.
Medical subject headings
- Adaptive Immunity
- Immunity, Innate
- Inflammasomes
- Lymph Nodes
- Macrophages
- Poxviridae Infections
- T-Lymphocytes