Hyperthyroidism Presenting With Pathologic Fractures.
case_report · Level V
Where this comes from
- Record sourced from PubMed, PMID 26746406.
- Also identified by DOI 10.1542/peds.2015-0169 and PMC identifier 4822824.
- No licence information is recorded for this record.
- Because redistribution is not established, this page shows the abstract only. Follow the links below for the full text.
Abstract
Previous studies have shown that thyroid hormone directly stimulates bone resorption in in vitro organ culture, and in adults excess thyroid hormone is associated with decreased bone mineral density. There are limited data in children regarding the effect of hyperthyroidism on bone metabolism and even fewer instances in the literature of hyperthyroidism presenting with bone demineralization and fracture. We report a case of an 11-year-old boy with undiagnosed hyperthyroidism presenting with fractures and osteoporosis. This case emphasizes the importance of maintaining a broad differential diagnosis when a patient presents with a pathologic fracture.
Medical subject headings
- Graves Disease
- Osteoporosis
- Osteoporotic Fractures
- Radius Fractures
- Spinal Fractures
- Thoracic Vertebrae