Lost in Translation: Preserving Satellite Cell Function with Global Translational Control.

Eliazer, Susan; Brack, Andrew S · Cell Stem Cell · 2016

editorial · Level V

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Abstract

Quiescence is highly regulated to preserve stem cell function. In this issue of Cell Stem Cell, Zismanov et al. (2016) show that P-eIF2α, a translational initiation factor, reinforces the quiescent state of muscle stem cells by safeguarding against cell-cycle entry and lineage progression.

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