Improving Stem Cell Therapeutics with Mechanobiology.

Shin, Jae-Won; Mooney, David J · Cell Stem Cell · 2016

review · Level V

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Abstract

In recent years, it has become clear that mechanical cues play an integral role in maintaining stem cell functions. Here we discuss how integrating physical approaches and engineering principles in stem cell biology, including culture systems, preclinical models, and functional assessment, may improve clinical application in regenerative medicine.

Medical subject headings