Prognostic assessment of IgA nephropathy: how much does histology add?

Abstract

IgA nephropathy exhibits a widely varying clinical course from asymptomatic urinary abnormalities to rapidly progressive renal failure. Determining the prognosis based on parameters obtained very early in the course of disease is of central importance in clinical decision making. Barbour et al. assessed whether adding biopsy findings to clinical parameters obtained at first presentation improves the predictive power.