Approach to asymptomatic creatine kinase elevation.

Moghadam-Kia, Siamak; Oddis, Chester V; Aggarwal, Rohit · Cleve Clin J Med · 2016

other · Level V

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Abstract

How to manage a patient who has an elevated serum creatine kinase (CK) level but no or insignificant muscle-related signs and symptoms is a clinical conundrum. The authors provide a systematic approach, including repeat testing after a period of rest, defining higher thresholds over which pursuing a diagnosis is worthwhile, and evaluating for a variety of nonneuromuscular causes. They also outline a workup for neuromuscular causes.

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