The NLRP1-IL18 Connection: A Stab in the Back of Obesity-Induced Inflammation.
Where this comes from
- Record sourced from PubMed, PMID 26771112.
- Also identified by DOI 10.1016/j.cmet.2015.12.014.
- No licence information is recorded for this record.
- Because redistribution is not established, this page shows the abstract only. Follow the links below for the full text.
Abstract
IL-18 has been reported to counteract obesity and metabolic syndrome, though the underlying mechanisms remain unclear. In this issue, Masters and colleagues describe how NLRP1 inflammasome induces IL-18 production in fat, solving not only an important biological mechanism, but also opening the door for therapeutic approaches (Murphy et al., 2016).
Medical subject headings
- Inflammasomes
- Interleukin-18