Parameters determining the efficacy of CD32 to inhibit activation of FcεRI in human basophils.
other · Level V
Where this comes from
- Record sourced from PubMed, PMID 26774660.
- Also identified by DOI 10.1016/j.jaci.2015.10.043 and PMC identifier 4826808.
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Abstract
The conditions needed to readily observe the role of CD32 in modulating IgE-mediated secretion are enumerated and include consideration of IgG subclass, with a possible emphasis on IgG3, antibody:antigen ratios, but with no evidence that polymorphic variants of CD32 influence its function.
Medical subject headings
- Basophils
- Immunoglobulin E
- Immunoglobulin G
- Receptors, IgE
- Receptors, IgG