Polyanionic Macromolecular Prodrugs of Ribavirin: Antiviral Agents with a Broad Spectrum of Activity.

Hinton, Tracey M; Zuwala, Kaja; Deffrasnes, Celine; Todd, Shawn; Shi, Shuning; Marsh, Glenn A; Dearnley, Megan; Wohl, Benjamin M et al. · Adv Healthc Mater · 2016

basic_science · Level V

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Abstract

Macromolecular prodrugs are developed as multiarmed agents against diverse viral pathogens. Lead candidates inhibit infectivity and replication of HIV, Ebola, influenza, measles, RSV, etc-thus being broad-spectrum antiviral agents.

Medical subject headings