Sensing Conductive Hydrogels for Rapid Detection of Cytokines in Blood.

Shin, Dong-Sik; Matharu, Zimple; You, Jungmok; Siltanen, Christian; Vu, Tam; Raghunathan, Vijay Krishna; Stybayeva, Gulnaz; Hill, Ashley E et al. · Adv Healthc Mater · 2016

basic_science · Level V

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Abstract

Conducting polymer hydrogel is fabricated atop gold or ITO electrodes and is functionalized with monoclonal antibodies. Binding of interferon-γ molecules causes redox properties of conductive hydrogel to change in a concentration-dependent fashion without the need for washing or sample handling steps. This conductive hydrogel remains functional in a fouling media such as whole blood.

Medical subject headings