Epithelial-to-mesenchymal transition of tubular epithelial cells in renal fibrosis: a new twist on an old tale.
review · Level V
Where this comes from
- Record sourced from PubMed, PMID 26806826.
- Also identified by DOI 10.1016/j.kint.2015.12.025.
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Abstract
Recent publications have questioned whether epithelial-to-mesenchymal transition of tubular epithelial cells is an important contributor to renal fibrosis. Two recent publications describe an intratubular epithelial-to-mesenchymal transition-like program of epithelial cell dedifferentiation that may contribute to the recruitment or proliferation of interstitial myofibroblasts after kidney injury.
Medical subject headings
- Epithelial-Mesenchymal Transition
- Kidney Diseases