Hidden in the mist no more: physical force in cell biology.

Wang, Karin; Cai, Li-Heng; Lan, Bo; Fredberg, Jeffrey J · Nat Methods · 2016

Level V

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Abstract

To drive its migration through a fibrillar matrix—and thus to spread, invade or metastasize—a cancer cell must exert physical forces. The first visualization of these forces in three dimensions reveals surprising migration dynamics.

Medical subject headings