Photocrosslinking of Silk Fibroin Using Riboflavin for Ocular Prostheses.
basic_science · Level V
Where this comes from
- Record sourced from PubMed, PMID 26821561.
- Also identified by DOI 10.1002/adma.201504527.
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Abstract
A novel method to photocrosslink silk fibroin protein is reported, using riboflavin (vitamin B2) as a photoinitiator and the mechanism of crosslinking is determined. Exposure of riboflavin-doped liquid silk solution to light results in the formation of a transparent, elastic hydrogel. Several applications for this new material are investigated including corneal reshaping to restore visual acuity and photolithography.
Medical subject headings
- Biocompatible Materials
- Fibroins
- Riboflavin