Epigenetic ON/OFF Switches for Obesity.
review · Level V
Where this comes from
- Record sourced from PubMed, PMID 26824648.
- Also identified by DOI 10.1016/j.cell.2016.01.006.
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Abstract
Heritable epigenetic mechanisms might contribute to the worldwide increase in the prevalence of obesity. Dalgaard et al. identify an epigenetic molecular switch that controls body weight control. The discovery suggests the existence of mammalian polyphenism in energy metabolism and might have implications for strategies to limit the obesity epidemic.
Medical subject headings
- Epigenesis, Genetic
- Haploinsufficiency
- Nuclear Proteins
- Obesity
- Repressor Proteins
- Thinness