The Importance of Timing.
basic_science · Level V
Where this comes from
- Record sourced from PubMed, PMID 26824651.
- Also identified by DOI 10.1016/j.cell.2016.01.010.
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Abstract
Building a nervous system requires a precise sequence of genetic transitions, mediated in part by the temporal and spatial regulation of transcription factors. Quan et al. add to our understanding of this regulation by describing an evolutionarily conserved post-translational mechanism that rapidly extinguishes proneural protein activity in neural precursors.
Medical subject headings
- Basic Helix-Loop-Helix Proteins
- Neurogenesis