TruSPAdes: barcode assembly of TruSeq synthetic long reads.
basic_science · Level V
Where this comes from
- Record sourced from PubMed, PMID 26828418.
- Also identified by DOI 10.1038/nmeth.3737.
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Abstract
The recently introduced TruSeq synthetic long read (TSLR) technology generates long and accurate virtual reads from an assembly of barcoded pools of short reads. The TSLR method provides an attractive alternative to existing sequencing platforms that generate long but inaccurate reads. We describe the truSPAdes algorithm (http://bioinf.spbau.ru/spades) for TSLR assembly and show that it results in a dramatic improvement in the quality of metagenomics assemblies.
Medical subject headings
- Algorithms
- Chromosome Mapping
- DNA Barcoding, Taxonomic
- High-Throughput Nucleotide Sequencing
- Sequence Analysis, DNA
- Software