Higher cough flow is associated with lower risk of pneumonia in acute stroke.
prospective_cohort · Level II
Where this comes from
- Record sourced from PubMed, PMID 26834183.
- Also identified by DOI 10.1136/thoraxjnl-2015-207810.
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Abstract
There is little available evidence to demonstrate how cough strength mediates the risk of aspiration-related pneumonia in acute stroke. Our secondary analysis of trial data indicates that risk of pneumonia reduces with increasing peak cough flow (PCF) of voluntary cough (OR 0.994 for each 1 L/min increase in PCF, 95% CI 0.988 to 1.0, p=0.035); and to a lesser degree with increasing PCF of reflex cough (OR 0.998 for each 1 L/min increase in PCF, 95% CI 0.992 to 1.004, p=0.475). These data serve hypothesis generation. Further studies are needed to confirm these findings and validate their clinical utility. ISRCTN40298220 (post-results).
Medical subject headings
- Cough
- Peak Expiratory Flow Rate
- Pneumonia, Aspiration
- Stroke