pH-Responsive Fe(III)-Gallic Acid Nanoparticles for In Vivo Photoacoustic-Imaging-Guided Photothermal Therapy.

Zeng, Jianfeng; Cheng, Ming; Wang, Yong; Wen, Ling; Chen, Ling; Li, Zhen; Wu, Yongyou; Gao, Mingyuan et al. · Adv Healthc Mater · 2016

basic_science · Level V

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Abstract

pH-responsive biocompatible Fe(III)-gallic acid nanoparticles with strong near-infrared absorbance are very stable in mild acidic conditions, but easily decomposed in neutral conditions, which enables the nanoparticles to be stable in a tumor and easily metabolized in other organs, thus providing a safe nanoplatform for in vivo photoacoustic imaging/photothermal therapy theranostic applications.

Medical subject headings