Perfluorocarbon-Loaded Hollow Bi2Se3 Nanoparticles for Timely Supply of Oxygen under Near-Infrared Light to Enhance the Radiotherapy of Cancer.
basic_science · Level V
Where this comes from
- Record sourced from PubMed, PMID 26848553.
- Also identified by DOI 10.1002/adma.201504617.
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Abstract
Hollow Bi2 Se3 nanoparticles prepared by a cation exchange method are loaded with perfluorocarbon as an oxygen carrier. With these nanoparticles, a promising concept is demonstrated to enhance radiotherapy by not only using their X-ray-absorbing ability to locally concentrate radiation energy in the tumor, but also employing near-infrared light to trigger burst release of oxygen from the nanoparticles to overcome hypoxia-associated radio-resistance.
Medical subject headings
- Bismuth
- Fluorocarbons
- Infrared Rays
- Metal Nanoparticles
- Neoplasms
- Organoselenium Compounds
- Oxygen