Naive versus Primed: It's Now Three-Dimensional.
editorial · Level V
Where this comes from
- Record sourced from PubMed, PMID 26849300.
- Also identified by DOI 10.1016/j.stem.2016.01.014.
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Abstract
We are only beginning to understand the higher-order chromatin structure of pluripotent stem cells and its relevance to cell fate. Three recent studies used different approaches to reconstruct the 3D chromatin landscape of naive and primed pluripotent cells, unveiling common features as well as differences between these two states.
Medical subject headings
- Cell Differentiation
- Pluripotent Stem Cells