Time to Relax: Mechanical Stress Release Guides Stem Cell Responses.
editorial · Level V
Where this comes from
- Record sourced from PubMed, PMID 26849301.
- Also identified by DOI 10.1016/j.stem.2016.01.020.
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Abstract
Stem cells integrate spatiotemporal cues, including the mechanical properties of their microenvironment, into their fate decisions. Chaudhuri et al. (2015) show that the ability of the extracellular matrix to dissipate cell-induced forces, referred to as stress-relaxation, is a key mechanical signal influencing stem cell fate and function.
Medical subject headings
- Mesenchymal Stem Cells