Mitochondrial Damage Induces Senescence with a Twisted Arm.
editorial · Level V
Where this comes from
- Record sourced from PubMed, PMID 26863485.
- Also identified by DOI 10.1016/j.cmet.2016.01.012.
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Abstract
Cellular senescence is a damage response characterized by a stable cell-cycle arrest and an intense secretion of cytokines. In this issue of Cell Metabolism, Wiley et al. (2016) report that, in the case of mitochondrial damage, senescence occurs with an atypical secretory phenotype, in both adipose tissue and skin.
Medical subject headings
- Arm
- DNA Damage