Endothelial chimerism in chronic sclerotic-type chronic graft-versus-host disease (GVHD) and GVHD-associated angiomatosis.

Kaffenberger, B H; Zhang, E; Duncan, J R; Jaglowski, S; Klisovic, R B; Devine, S M; Wong, H K; Gru, A A · Br J Dermatol · 2016

case_report · Level V

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Abstract

Graft-versus-host disease-associated angiomatosis (GVHD-AA) is an uncommon manifestation of chronic GVHD consisting of friable vascular proliferations. Using fluorescence in situ hybridization, we demonstrate the presence of donor-derived endothelial cells within areas of GVHD-AA. This is the first documented occurrence of a benign neoplastic growth in relationship to a form of chronic GVHD.

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