Switching of carbohydrate nanofibers for regulating cell proliferation.

Na, Guangren; He, Ying; Kim, Yongju; Lee, Myongsoo · Soft Matter · 2016

basic_science · Level V

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Abstract

We report switchable, fluorescent carbohydrate nanofibers formed through the self-assembly of aromatic rod amphiphiles with a combination of mannose epitopes and thermoresponsive oligoether dendrons. The carbohydrate nanofibers undergo reversible switching between carbohydrate-exposed and hidden states on their surface in response to a thermal signal, and have the ability to regulate cell proliferation.

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