Sex Differences in Risk Factors and Natural History of Oral Human Papillomavirus Infection.
prospective_cohort · Level II
Where this comes from
- Record sourced from PubMed, PMID 26908748.
- Also identified by DOI 10.1093/infdis/jiw063 and PMC identifier 9136851.
- No licence information is recorded for this record.
- Because redistribution is not established, this page shows the abstract only. Follow the links below for the full text.
Abstract
Oral human papillomavirus genotype 16 (HPV16) infection causes oropharyngeal squamous cell carcinoma (SCC), and the prevalence of oropharyngeal SCC is higher among men than women in the United States. In a cohort study of oral HPV infection among 409 individuals aged 18-25 years, the risk among men but not among women significantly increased as the number of recent (ie, within the prior 3 months) oral sex partners increased (Pinteraction = .05). In contrast, the risk among women but not among men significantly decreased as the lifetime number of vaginal sex partners increased (Pinteraction = .037). Men were also significantly less likely than women to clear oral HPV infection. Our data contribute to understanding sex differences in risk for HPV-positive oropharyngeal SCC. NCT00994019.
Medical subject headings
- Carcinoma, Squamous Cell
- Human papillomavirus 16
- Mouth Diseases
- Oropharyngeal Neoplasms
- Papillomavirus Infections