Norovirus Infections Occur in B-Cell-Deficient Patients.

Brown, Julianne R; Gilmour, Kimberly; Breuer, Judith · Clin Infect Dis · 2016

retrospective_cohort · Level III

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Abstract

Norovirus incidence was compared between severe combined immunodeficiency children with (n = 10) and without (n = 8) B cells. 60% of B+ and 63% of B- patients developed norovirus infections therefore norovirus replication in B lymphocytes is not essential for infection.

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