Controlled self-assembly of biomolecular rods on structured substrates.
basic_science · Level V
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- Record sourced from PubMed, PMID 26917247.
- Also identified by DOI 10.1039/c6sm00073h.
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Abstract
We report on the evaporative self-assembly and orientational ordering of semi-flexible spherocylindrical M13 phages on asymmetric stranded webs of thin amorphous carbon films. Although the phages were dispersed with a low concentration in the isotropic phase, the substrate edges induced nematic ordering and bending of the phages. As revealed by transmission electron microscopy, phages were aligned parallel to the curved substrate edges. This two-dimensional self-assembly on structured substrates opens a new route to the design of structures of orientationally ordered semi-flexible biomacromolecules.
Medical subject headings
- Bacteriophage M13