Getting a Grip on Microtubules.

Schaletzky, Julia; Rape, Michael · Cell · 2016

editorial · Level V

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Abstract

Posttranslational modifications control microtubule behavior, yet assigning roles to particular signals was hampered by lack of defined in vitro systems. In this issue of Cell, Valenstein and Roll-Mecak establish a biochemical platform to interrogate consequences of microtubule polyglutamylation, thereby providing important insights into the specificity and quantitative nature of cellular information transfer.

Medical subject headings