Revisiting Management of Pediatric Brain Tumors with New Molecular Insights.
editorial · Level V
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- Record sourced from PubMed, PMID 26919424.
- Also identified by DOI 10.1016/j.cell.2016.02.030.
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Abstract
Pediatric central nervous system primitive neuro-ectodermal brain tumors (CNS-PNETs) are rare tumors with ill-defined biological features. In this issue of Cell, Sturm et al. used state-of-the-art methods to interrogate these tumors' biology. Their integrated molecular analyses led them to propose a new molecular classification, with four new entities identified, that should get oncologists' attention.
Medical subject headings
- Central Nervous System Neoplasms
- DNA Methylation
- Neuroectodermal Tumors