Photolytic Protein Aggregates: Versatile Materials for Controlled Release of Active Proteins.
basic_science · Level V
Where this comes from
- Record sourced from PubMed, PMID 26945901.
- Also identified by DOI 10.1002/adhm.201500957.
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Abstract
Photolytic protein aggregates are developed as a facile and versatile platform for light-induced release of active proteins. The proteins modified with biotin through a photo-cleavable linker rapidly form aggregates with streptavidin and biotinylated functional molecules simply by mixing. Light irradiation releases active proteins from the aggregates in high yields, and light-induced uptake of drug-modified transferrin into living cells is successfully demonstrated.
Medical subject headings
- Photolysis
- Protein Aggregation, Pathological
- Transferrin