Predictive Biomarkers for PD-1 Axis Therapies: The Hidden Treasure or a Call for Research.

Schalper, Kurt A; Kaftan, Edward; Herbst, Roy S · Clin Cancer Res · 2016

editorial · Level V

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Abstract

Blockade of the PD-1 axis has emerged as an effective anticancer immunotherapy against various tumor types. Diverse studies have identified biomarkers associated with response to these therapies. However, the clinical use of such tests is limited by their variable performance and restricted understanding of their biologic significance. Clin Cancer Res; 22(9); 2102-4. ©2016 AACRSee related article by Ock et al., p. 2261.

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