Deconstructing Dietary Restriction: A Case for Systems Approaches in Aging.
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- Record sourced from PubMed, PMID 26959179.
- Also identified by DOI 10.1016/j.cmet.2016.02.018 and PMC identifier 5240043.
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Abstract
Dietary restriction is a robust and conserved intervention to slow aging and extend lifespan. In this issue of Cell Metabolism, Hou et al. (2016) use a systems biology approach in C. elegans to uncover key molecular nodes underlying the transcriptomic response to dietary restriction and predict novel regulators of lifespan.
Medical subject headings
- Caenorhabditis elegans
- Longevity