Transferring Fragments of Paternal Metabolism to the Offspring.
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- Record sourced from PubMed, PMID 26959182.
- Also identified by DOI 10.1016/j.cmet.2016.02.014.
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Abstract
Paternal diet influences offspring metabolism, yet the underlying epigenetic mechanisms are unclear. Recently, Chen et al. (2016) and Sharma et al. (2016) identified tRNA fragments in sperm and the male reproductive tract as possible inherited factors altered by paternal diet that lead to gene misexpression and altered metabolism in offspring.