Reverse Engineering Human Pathophysiology with Organs-on-Chips.

Ingber, Donald E · Cell · 2016

basic_science · Level V

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Abstract

While studies of cultured cells have led to new insights into biological control, greater understanding of human pathophysiology requires the development of experimental systems that permit analysis of intercellular communications and tissue-tissue interactions in a more relevant organ context. Human organs-on-chips offer a potentially powerful new approach to confront this long-standing problem.

Medical subject headings