Calcium oxalate precipitation by diffusion using laminar microfluidics: toward a biomimetic model of pathological microcalcifications.
basic_science · Level V
Where this comes from
- Record sourced from PubMed, PMID 26974287.
- Also identified by DOI 10.1039/c6lc00197a.
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Abstract
The effect of mixing calcium and oxalate precursors by diffusion at miscible liquid interfaces on calcium oxalate crystalline phases, and in physiological conditions (concentrations and flow rates), is studied using a microfluidic channel. This channel has similar dimensions as the collection duct in human kidneys and serves as a biomimetic model in order to understand the formation of pathological microcalcifications.
Medical subject headings
- Biomimetics
- Calcinosis
- Calcium Oxalate
- Chemical Precipitation
- Diffusion
- Kidney
- Microfluidic Analytical Techniques