Controlled assembly of heterotypic cells in a core-shell scaffold: organ in a droplet.
basic_science · Level V
Where this comes from
- Record sourced from PubMed, PMID 26999495.
- Also identified by DOI 10.1039/c6lc00231e and PMC identifier 4829496.
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Abstract
This paper reports a droplet-based microfluidic approach to fabricate a large number of monodisperse, portable microtissues, each in an individual drop. We use water-water-oil double emulsions as templates and spatially assemble hepatocytes in the core and fibroblasts in the shell, forming a 3D liver model in a drop.
Medical subject headings
- Microfluidics
- Tissue Scaffolds