Metabolic control of arthritis: Switch pathways to treat.
editorial · Level V
Where this comes from
- Record sourced from PubMed, PMID 27009266.
- Also identified by DOI 10.1126/scitranslmed.aaf4953.
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Abstract
A shunting of glucose metabolism to the pentose phosphate pathway in rheumatoid arthritis T cells causes exhaustion of oxidants, enhanced cell proliferation, and differentiation toward the T helper 1 (TH1) and TH17 programs (Yanget al, this issue).
Medical subject headings
- Arthritis, Rheumatoid
- Th1 Cells