Overview of Biologics.

Anand, Neel · Spine (Phila Pa 1976) · 2016

review · Level V

Where this comes from

Abstract

Biologics in the appropriate biomechanical environment provide viable bone graft substitutes for repair of injured bone while promoting bone formation and osseointegration. Surgeons must recall the basics of bone structure, the principles of Wolff's law, and the components and steps of new bone formation to optimize the fusion environment and to maximize patient outcomes.

Medical subject headings